Research: Clear+Updated 15 days ago

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Several studies have linked sulforaphane to improvements in “verbal communication.” 

1. Ou et al. (2024) https://pubmed.ncbi.nlm.nih.gov/36427174/ - Demonstrated significant improvements in verbal communication skills in children with ASD, noted in various language-related assessments and parent-reported outcomes.
2. Zimmerman et al. (2021) https://pubmed.ncbi.nlm.nih.gov/34034808/ - Found notable improvements in verbal communication, linked to changes in specific metabolites, suggesting a biochemical pathway for sulforaphane’s effects.
3. Singh et al. (2014) https://doi.org/10.1073/pnas.1416940111 - Provided evidence of significant improvements in both expressive and receptive language skills in children with ASD treated with sulforaphane.
4. Bent et al. (2018) https://doi.org/10.1186/s13229-018-0218-4 - Reported that children with ASD who showed clinical improvements, including better verbal communication, had distinct changes in their urinary metabolite profiles, suggesting a metabolic mediation of sulforaphane’s impact.
5. Magner et al. (2023) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920098/ - Demonstrated significant improvements in verbal communication among children with ASD through various clinician-rated scales.
6. Yang et al. (2024) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10800504/ - Suggested that improvements in verbal communication might be related to sulforaphane’s impact on the gut microbiome, indicating potential multifaceted mechanisms.
7. Momtazmanesh et al. (2020) https://pubmed.ncbi.nlm.nih.gov/32347624/ - Focused on sulforaphane for irritability in children with ASD. Some secondary improvements in verbal communication were observed but not the primary focus.